Berger J. IgA glomerular deposits in renal disease. Transplant. Proc. 1:939-44, 1969
نویسنده
چکیده
glomerulonephritis, since then called “Maladie de Berger,” and/or immunoglobulin A (IgA) nephropathy. Using a direct immunofluorescence technique, Jean Berger, a French pathologist, identified the presence of mesangial IgA deposits. This test remains to date the only means to diagnose what has been recognized to be the most common glomerulonephritis. [The SCI indicates that this paper has been cited in more than 410 publications, making it the most-cited paper published in this journal.]
منابع مشابه
[IgA nephropathy].
IgA nephropathy is glomerular disease first described in 1968 by Berger, named after him Morbus Berger. The disease is characterized by the presence of IgA dominant or codominant immunoglobulin deposits in glomerular mesangium which can be demonstrated by immunofluorescence. Clinical manifestations of IgA nephropathy in the majority of cases is hematuria which can be macro or microscopic, isola...
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9. Babbs C, Warnes TW, Torrance HB, Ballardie FW. IgA nephro17. Lomax-Smith JD, Zabrowarny LA, Howarth GS, Seymour pathy in non-cirrhotic portal hypertension. Gut 1990; 32: AAE, Woodroffe AJ. The immunochemical characterisation of 225–226 mesangial IgA deposits. Am J Pathol 1983; 113: 359–364 10. Berger J, Yaneva H, Nabarra B. Glomerular changes in patients 18. Giron JA, Alvarez-Mon M, Menéndez...
متن کاملRecurrent haematuria and mesangial IgA deposition.
Six patients are described in whom recurrent haematuria was associated with IgA deposits in the glomerular mesangium. These patients conform closely to the nephropathy described by Berger. The condition can only be definitely diagnosed by immunofluorescence techniques. These six patients were diagnosed in one renal unit within 18 months and, despite the absence of reports from British units, th...
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BACKGROUND Various renal manifestations are known to develop in patients with liver disease, including chronic hepatitis and cirrhosis. CASE PRESENTATION We evaluated renal disease in two 47-year-old Japanese men with liver cirrhosis and chronic alcoholism for 34 years and 27 years, respectively. Renal biopsy demonstrated massive wire loop-like deposits in the subendothelial space of the glom...
متن کاملDevelopment of IgA nephropathy 14 years after diagnosis of membranous nephropathy.
Membranous nephropathy is characterized clinically by nephrotic proteinuria and pathologically by the presence of electron dense IgG deposits below the epithelium in glomerular basement membrane. Although about 20–30% of cases of membranous nephropathy are secondary, the majority of cases are idiopathic. The clinical features of IgA nephropathy include haematuria and proteinuria. Although IgA n...
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